Status:
UNKNOWN
Impact of Oral Glucose Tolerance Test on Extent of Hemoglobin Glycation
Lead Sponsor:
Urs E. Nydegger
Collaborating Sponsors:
Labormedizinisches Zentrum Dr. Risch
Conditions:
Blood Glucose, High
Oral Hypoglycaemic Overdose
Eligibility:
All Genders
5-40 years
Brief Summary
The glycation extent of human hemoglobin is under control of the Maillard reaction, a chemical interaction between an amino acide and a reducing sugar. About 5% ( 31.1 mmol/mol) of hemoglobin molecule...
Detailed Description
Medical laboratory assays for delineation of impaired glucose metabolism and overt diabetes mellitus, beyond measurement of (fasting) blood serum or plasma glucose levels, include extent of hemoglobin...
Eligibility Criteria
Inclusion
- apparently healthy subjects or subjects supposedly experiencing a metabolic disease (e.g. prediabetes) Subjects with asked for fasting blood glucose
Exclusion
- current steroid use thyroid dysfunction (free-thyroxin levels \< 9 or \> 19 pmol/L, hsCRP \> 10 mg/L hospitalized
Key Trial Info
Start Date :
September 1 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
September 30 2021
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04018430
Start Date
September 1 2019
End Date
September 30 2021
Last Update
July 12 2019
Active Locations (1)
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1
University of Bern
Bern, Canton of Bern, Switzerland, 3000