Status:
UNKNOWN
The Impact of Endoscopic Pituitary Surgery on Nasal Function
Lead Sponsor:
Zhebao Wu
Collaborating Sponsors:
Shanghai Zhongshan Hospital
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Conditions:
Pituitary Tumor
Endoscopic Surgery
Eligibility:
All Genders
18-65 years
Brief Summary
The aim of this study is to determine the impact of endoscopic transsphenoidal pituitary surgery on nasal function using a numerical simulation and to compare the difference between two kinds of trans...
Detailed Description
Neuroendoscopic surgery is the first treatment for most pituitary adenoma patients. Because transsphenoidal surgery exploits the nasal corridor and paranasal sinuses to reach the skull base, sinonasal...
Eligibility Criteria
Inclusion
- Enhanced MRI shows a pituitary tumor
- Endoscopic surgery is required according to the pituitary tumor treatment guidelines.
- Karnofsky performance status ≥ 70.
- The patient has signed the informed consent.
Exclusion
- Patients who have undergone previous transsphenoidal surgery or other nasal surgery.
- Patients who had a history of nasal tumors.
- Patients who had a history of severe head or face trauma.
- Patients with congenital sinus malformation.
- Pregnant or lactating women.
- Patients with serious systemic diseases without control.
- Patients with poor compliance, who cannot implement the program strictly.
Key Trial Info
Start Date :
July 25 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2021
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT04018963
Start Date
July 25 2019
End Date
December 31 2021
Last Update
October 9 2020
Active Locations (1)
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1
Ruijin Hospital
Shanghai, Shanghai Municipality, China, 200025