Status:

COMPLETED

Carbohydrate Intake and Gut Hormone Release During Exercise

Lead Sponsor:

Imperial College London

Conditions:

Obesity

Eligibility:

MALE

18-40 years

Phase:

NA

Brief Summary

It is well known that following a single session of moderate-to-high intensity exercise individuals experience a temporary suppression of hunger and a delay in the commencement of eating. This effect ...

Detailed Description

It is well established that following an acute bout of moderate-to-high intensity exercise individuals experience a transient suppression of hunger and a delay in the commencement of eating - a phenom...

Eligibility Criteria

Inclusion

  • Male
  • Age between 18-40 years (inclusive)
  • Body mass index (BMI) of 18-30 kg/m2
  • Willingness and ability to give written informed consent and willingness and ability to understand, to participate and to comply with the study requirements

Exclusion

  • Abnormal ECG
  • Screening blood results outside of normal reference values
  • Current smokers
  • Current or history of substance abuse and/or excess alcohol intake
  • Diabetes
  • Cardiovascular disease
  • Cancer
  • Gastrointestinal disease e.g. inflammatory bowel disease or irritable bowel syndrome
  • Kidney disease
  • Liver disease
  • Pancreatitis
  • Started new medication within the last 3 months likely to interfere with energy metabolism, appetite regulation and hormonal balance, including: anti-inflammatory drugs or steroids, antibiotics, androgens, phenytoin, erythromycin or thyroid hormones.
  • Participation in a research study in the 12 week period prior to entering this study.
  • Any blood donation within the 12 week period prior to entering this study

Key Trial Info

Start Date :

February 21 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 12 2020

Estimated Enrollment :

12 Patients enrolled

Trial Details

Trial ID

NCT04019418

Start Date

February 21 2019

End Date

February 12 2020

Last Update

August 9 2024

Active Locations (1)

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Imperial Clinical Research Facility

London, United Kingdom, W12 0HS