Status:
COMPLETED
Neurophysiology of Prophylactic Treatment in Migraine
Lead Sponsor:
University Medicine Greifswald
Conditions:
Migraine
Eligibility:
All Genders
18+ years
Brief Summary
This study aims to improve the pathophysiological understanding of migraine in in a longitudinal observational study investigating changes of established neurophysiological and imaging parameters in l...
Eligibility Criteria
Inclusion
- Inclusion Criteria (migraineurs):
- episodic migraine according to ICHD (international classification of headache disorders)-3 criteria
- headache documented over at least 3 months through a headache calender
- scheduled for prophylactic therapy of their migraine
- Exclusion Criteria (migraineurs):
- history of chronic migraine
- current medication-overuse headache
- neurological or psychiatric diagnosis other than headaches
- chronic intake of central nervous system active drugs (antidepressants, antipsychotics etc.)
- contraindications for magnetic resonance imaging
- contraindications for transcranial magnetic stimulation
- Inclusion criteria (controls):
- not more than 3 years younger or older than matched control
- gender similar to matched control
- menstrual cycle equal to matched control (if female)
- exclusion criteria (controls):
- more than 1 headache day/month
- history of migraine
Exclusion
Key Trial Info
Start Date :
January 29 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 2 2021
Estimated Enrollment :
44 Patients enrolled
Trial Details
Trial ID
NCT04019496
Start Date
January 29 2019
End Date
May 2 2021
Last Update
May 27 2021
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Department of Neurology
Greifswald, Mecklenburg-Vorpommern, Germany, 17475