Status:

UNKNOWN

The Influence of Different Thyroid Autoantibodies on Thyroid Function and Pregnancy Outcome After Assisted Reproductive Technology

Lead Sponsor:

Universitair Ziekenhuis Brussel

Conditions:

Fertility Disorders

Thyroid Dysfunction

Eligibility:

FEMALE

18-36 years

Phase:

NA

Brief Summary

The influence of thyroid autoantibodies on thyroid function in pregnancy after fertility treatment is not well known. The objectives of the present study are: 1. To monitor the course of thyroid fun...

Detailed Description

Thyroid autoantibodies and / or abnormal thyroid function are associated with fertility problems. A possible explanation for this is, an influence of thyroid autoantibodies on the functioning of the ...

Eligibility Criteria

Inclusion

  • first cycle of assisted reproductive technology with follow up of thyroid function at the Universitair Ziekenhuis Brussel
  • age \>= 18 and \<= 36 years
  • body mass index between 18 and 35

Exclusion

  • Patients with clinical thyroid dysfunction
  • Patients being treated with levothyroxine or antithyroid drugs
  • Patients being treated with glucocorticosteroids
  • Patients undergoing in vitro maturation or preimplantation genetic testing.
  • Poor responders during IVF/ICSI stimulation, using the Bologna criteria

Key Trial Info

Start Date :

January 1 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2022

Estimated Enrollment :

900 Patients enrolled

Trial Details

Trial ID

NCT04019509

Start Date

January 1 2019

End Date

September 1 2022

Last Update

July 15 2019

Active Locations (1)

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UZ Brussel

Brussels, Belgium, 1090