Status:
COMPLETED
The Effect of a Ketogenic Diet on the Exercise Induced Immune Response
Lead Sponsor:
Wageningen University
Conditions:
Upper Respiratory Tract Infections
Eligibility:
MALE
18-45 years
Phase:
NA
Brief Summary
comparing the exercise induced immune response after two weeks on a low carbohydrate (ketogenic) diet with the response after two weeks on a high carbohydrate diet.
Detailed Description
A cross-over intervention study, with a total duration of 6 weeks. An athlete follows a high, or low carbohydrate (ketogenic) diet. After 2 days a test day takes place where the athlete performs an ex...
Eligibility Criteria
Inclusion
- Male
- Age: 18 - 45 y
- BMI: 18.5 - 25 kg/m2
- Hb ≥ 8.5 mmol/L, determined with blood sample from finger tip
- Minimal of 3 hours of training per week, and a maximum of 10 hours
- DKTP (diphtheria, pertussis, tetanus and polio) vaccinated (for stimulation of isolated cells (PBMC's) with tetanus toxoid)
- No asthma medication and/or anti-inflammatory medication
- No use of immunosuppressive medication
- No flu and/or travel vaccinations in the 4 months before and during the study
- Able to be present and participate at all test days
- Willing and able to follow prescribed 2 times a diet for 2 weeks in a row
Exclusion
- Chronic illness
- Food allergies (e.g. nuts, gluten, avocado)
- Vegetarian diet
- Blood donations during study or in the 2 months prior to the study
- Use of immunosuppressive medication
- Flu and/or travel vaccination 4 months before and during the study
- Hb \< 8.5 mmol/L
- Working at "Human Nutrition" - Wageningen University
Key Trial Info
Start Date :
October 10 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 10 2019
Estimated Enrollment :
14 Patients enrolled
Trial Details
Trial ID
NCT04019730
Start Date
October 10 2018
End Date
October 10 2019
Last Update
December 19 2019
Active Locations (2)
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1
Division of Human Nutrition, Wageningen University
Wageningen, Gelderland, Netherlands, 6703 HA
2
Wageningen University and research
Wageningen, Gelderland, Netherlands, 6708 WE