Status:
COMPLETED
Real-time fMRI Neurofeedback in Patients With MCI
Lead Sponsor:
University of Bern
Collaborating Sponsors:
University of Zurich
Conditions:
Mild Cognitive Impairment
Eligibility:
All Genders
60-80 years
Phase:
NA
Brief Summary
Increased activity in the hippocampus (i.e., hyperactivity) during a fMRI memory task was found in patients with Mild Cognitive Impairment due to Alzheimer's disease (MCI). Those with increased hippoc...
Detailed Description
Alzheimer's disease (AD) is an insidious and progressive neurodegenerative disorder accompanied by extracellular deposits of beta-amyloid ( aβ) and the increase of cognitive dysfunctions. Several func...
Eligibility Criteria
Inclusion
- Intact activities of daily living
- Fluent in German
- Normal/corrected-to-normal vision
- Written informed consent
Exclusion
- Dementia
- Current/lifetime severe psychiatric or neurological disorder
- History of seizures
- Psychotropic medication
- Currently/lifetime drug or alcohol abuse
- Brain damage
- Magnetisable implants
Key Trial Info
Start Date :
July 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 31 2024
Estimated Enrollment :
84 Patients enrolled
Trial Details
Trial ID
NCT04020744
Start Date
July 1 2020
End Date
January 31 2024
Last Update
May 8 2024
Active Locations (2)
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1
SITEM (Swiss Institute for Translational and Entrepreneurial Medicine)
Bern, Switzerland, 3010
2
University of Zurich
Zurich, Switzerland, 8092