Status:
COMPLETED
Assessment of the Excitability of Spinal Motoneurons Using Stimulus-response Curves of the Bulbocavernosus Reflex
Lead Sponsor:
Pierre and Marie Curie University
Conditions:
Spasticity, Muscle
Eligibility:
All Genders
18-90 years
Brief Summary
Spasticity is commonly observed in neurological conditions such as Multiple Sclerosis and spinal cord injury. "Peripheral" spasticity, concerning in particular the striated muscles of the limbs is now...
Detailed Description
Spasticity defined by Lance in 1980 is "a motor disorder characterized by a velocity dependent increase in the tonic stretch reflexes (muscle tone) with exaggerated tendon jerks, resulting from hypere...
Eligibility Criteria
Inclusion
- 18 years old minimum
- Subjects with spinal cord injury or multiple sclerosis, requiring an electrophysiological and urodynamic explorations in our neuro-urology specialized department, with a strictly supra-sacral central neurological condition.
- Subjects with stress urinary incontinence (SUI) requiring perineal explorations including a cystometry and a perineal EMG.
Exclusion
- Subjects with peripheral neurological impairment (cauda equina syndrome, medullary cone syndrome, advanced diabetes)
- Subjects who received a treatment by injection of intra-detrusorian botulinum toxin in the last 6 months.
Key Trial Info
Start Date :
July 11 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 30 2019
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT04022187
Start Date
July 11 2019
End Date
September 30 2019
Last Update
February 18 2022
Active Locations (1)
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1
Department of neuro-urology, hôpital Tenon
Paris, France, 75020