Status:
UNKNOWN
Vascular Responses After Percutaneous Coronary Intervention With Stenting In Patients With Obstructive Sleep Apnea
Lead Sponsor:
Beijing Anzhen Hospital
Conditions:
Coronary Artery Disease
Obstructive Sleep Apnea of Adult
Eligibility:
All Genders
18-80 years
Brief Summary
Obstructive sleep apnea (OSA) is an increasingly common chronic disorder in adults. Compared to the general population, OSA occurs more often in patients with coronary artery disease (CAD), with a rep...
Eligibility Criteria
Inclusion
- 18 to 80 years old
- Patients undergoing PCI with stenting in at least one de novo lesion in a native coronary artery
- 3-vessel OCT was available visually (at least one pullback/vessel)
- Written informed consent
Exclusion
- Predominantly central sleep apnea (CSA, ≥50% central events or central apnea hypopnea index ≥10/h)
- Previous or current use of continuous positive airway pressure (CPAP)
- Cardiogenic shock (systolic arterial pressure \<90mmHg), congestive heart failure (NYHA or Killip≥3)
- STEMI within 1 week
- Prior PCI or CABG
- Chronic kidney disease \[eGFR\<60ml/(min\*1.73m2)\]
- Aortic-coronary ostial lesion
- Left main lesion
- Chronic total occlusion
- In-stent restenotic lesion
- A tortuous vessel and/or severely calcified lesion or severe stenosis and the OCT catheter could not pass across the lesion
- Massive residual thrombus on angiography despite thrombus aspiration or thrombectomy
- Planned elective PCI within 12 months
- Severe comorbidities: eg. malignancy (life expectancy \<2 years)
- Known or planned pregnancy
Key Trial Info
Start Date :
April 18 2018
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 31 2021
Estimated Enrollment :
84 Patients enrolled
Trial Details
Trial ID
NCT04022824
Start Date
April 18 2018
End Date
October 31 2021
Last Update
September 5 2021
Active Locations (1)
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1
Beijing Anzhen Hospital, Capital Medical University
Beijing, China, 100029