Status:

UNKNOWN

Effect of Proton Pump Inhibitor of Daily Use for One Month on Kidney Function Test

Lead Sponsor:

Assiut University

Conditions:

Proton Pump Inhibitor Allergy

Eligibility:

All Genders

18-65 years

Phase:

PHASE2

Brief Summary

The aim of this study to: evaluate the association between prolonged use of PPI and adverse renal outcomes on patients with normal renal function and others with abnormal renal function

Detailed Description

Proton pump inhibitors (PPIs) are one of the most widely used classes of drugs and are prescribed primarily for gastric acid-related diseases, eradication of Helicobacter pylori, and prevention of non...

Eligibility Criteria

Inclusion

  • patients with peptic ulcer disease or gastroesophagial reflux with normal l renal function
  • patients with peptic ulcer disease or gastroeosophagial reflux with abnormal renal function

Exclusion

  • 1- cigarette smoker: Cigarette smoking status was defined categorically as current,former, or never smoker at baseline.
  • 2-biabetic patients: diabetes mellitus is defined by a fasting blood glucose concentration \>\_ 126 mg/dl ,random glucose level of \>200 mg 3-patients take corticosteroid 4-patients with hypersensitivity to these drugs

Key Trial Info

Start Date :

November 1 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2021

Estimated Enrollment :

200 Patients enrolled

Trial Details

Trial ID

NCT04022837

Start Date

November 1 2019

End Date

December 1 2021

Last Update

July 17 2019

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