Status:

UNKNOWN

REWARD: Using the REtina as a Window To Detect Cardiac microvasculAR Dysfunction In Diabetes Mellitus

Lead Sponsor:

National Heart Centre Singapore

Collaborating Sponsors:

Singapore National Eye Centre

Conditions:

Retinopathy, Diabetic

Diastolic Dysfunction

Eligibility:

All Genders

21-120 years

Brief Summary

Retinopathy may be associated with diastolic dysfunction and/or coronary flow reserve in the heart, and albuminuria in diabetic patients. The objective of this study is to examine the cross-sectional ...

Detailed Description

Diabetes is a potent risk factor for macrovascular coronary disease, leading to systolic dysfunction and heart failure. More recently diabetic microvascular disease has been recognized to play a key r...

Eligibility Criteria

Inclusion

  • Age greater than equal to 21 years old

Exclusion

  • Known history of active eye lens or corneal opacity
  • Known allergy to eye drops
  • Kidney disease with estimated GFR \< 60
  • Pregnant or lactating women
  • Asthmatic status of the moderate persistent and above categories
  • Chronic obstructive pulmonary disease
  • Thyroid dysfunction

Key Trial Info

Start Date :

February 20 2018

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

May 31 2021

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT04025996

Start Date

February 20 2018

End Date

May 31 2021

Last Update

February 3 2021

Active Locations (1)

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National Heart Centre Singapore

Singapore, Singapore, 169609