Status:
RECRUITING
Uric Acid, Klotho and Salt Sensitivity in Young Adults Born Preterm
Lead Sponsor:
Wake Forest University Health Sciences
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Salt; Excess
Blood Pressure Disorders
Eligibility:
All Genders
22-33 years
Phase:
EARLY_PHASE1
Brief Summary
The purpose of this research is to learn about how salt in the diet influences blood pressure in young adults who were born prematurely.
Detailed Description
Premature birth is an emerging and important risk factor for hypertension and cardiovascular disease, as both preterm birth rates and infant survival increase worldwide. Hypertension and cardiovascula...
Eligibility Criteria
Inclusion
- Singleton birth
- Born at less than 34 weeks gestational age (preterm cohort)
- Born at greater than 36 weeks gestational age (term cohort)
Exclusion
- Twin birth
- Congenital anomalies or genetic syndromes
- Currently pregnant or breast feeding
- Subject-reported history of hypertension
- Current use of antihypertensive medications
- Active cancer
- Chronic kidney disease
- Heart failure
- Liver failure
Key Trial Info
Start Date :
September 2 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
June 1 2026
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT04026776
Start Date
September 2 2020
End Date
June 1 2026
Last Update
June 29 2025
Active Locations (1)
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1
Wake Forest University Health Sciences
Winston-Salem, North Carolina, United States, 27157