Status:
COMPLETED
Comparison Trial Between Two Repellent Products and a Positive Control Against Culicoides Nubeculosus Midges
Lead Sponsor:
ARCTEC
Conditions:
Midge Bites
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Comparison trial between two repellent products and a positive control against Culicoides nubeculosus midges. A single-centre laboratory setting study using healthy volunteers to test two insect repel...
Detailed Description
Mosquitoes, midges and other biting insects are vectors of extremely important diseases such as malaria, yellow fever, filariasis and many viruses and also may be of great nuisance value. The use of r...
Eligibility Criteria
Inclusion
- Able and willing to give fully informed consent;
- Able to understand and comply with the study procedures;
- Consider themselves to be in good general health;
- Male or female;
- Aged 18 to 65 years;
- Non-smokers or willing to refrain for 12 hours prior to and during each test;
- Willing to undergo a bite test with Culicoides nubeculosus midges with up to 72 hour follow-up.
Exclusion
- Suspected or known to be sensitive or allergic to midge bites;
- Participated in an interventional study (other than a biting insect challenge study) in the previous 3 months;
- Participated in a biting insect challenge study in the previous 72 hours;
- Aware of having any cardiovascular or respiratory disorder (whether active or inactive) (e.g. asthma);
- Individuals with localized skin disorders affecting the forearm;
- Allergic to any of the test product ingredients;
- Extensive tattooing or other conditions of the forearm which would make interpretation of the bite test results difficult;
- Women who are pregnant, nursing or intending to become pregnant;
- Previous anaphylaxis;
- Aware of having a compromised immune system;(an immune system that is temporarily or permanently incapable of working at full capacity);
- Phobia of flying insects;
- Travelled to a mosquito-borne disease endemic area in the last 3 months.
Key Trial Info
Start Date :
November 19 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 13 2019
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT04028180
Start Date
November 19 2018
End Date
February 13 2019
Last Update
July 22 2019
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Arctec at London School of Hygiene & Tropical Medicine
London, United Kingdom, WC1E 7HT