Status:

COMPLETED

Clinical Observation of Long-term Efficacy and Safety of Glycyrrhizic Acid Preparation in the Therapy of Autoimmune Liver Disease

Lead Sponsor:

Beijing Ditan Hospital

Conditions:

Autoimmune Liver Disease

Eligibility:

All Genders

18-75 years

Brief Summary

This study was a retrospective clinical observation cohort study. All patients with autoimmune liver disease treated with glycyrrhizic acid preparations in the Department of Liver Diseases, Department...

Detailed Description

This study was a retrospective clinical observation cohort study. All patients with autoimmune liver disease treated with glycyrrhizic acid preparations in the Department of Liver Diseases, Department...

Eligibility Criteria

Inclusion

  • 1\) Patients with autoimmune liver disease: All enrolled autoimmune liver diseases meet the diagnostic criteria of China's Consensus on Diagnosis and Treatment of Autoimmune Liver Disease (2015);
  • 2\) no hormones and / or immunosuppressants and other liver protection drugs;
  • 3\) Sign the written informed consent form.

Exclusion

  • 1\) Combine other hepatitis virus (HCV, HDV) infections;
  • 2\) viral liver disease;
  • 3\) HIV infection;
  • 4\) long-term alcohol abuse and / or other liver damage drugs;
  • 5\) mental illness;
  • 6\) Evidence of liver tumors (liver cancer or AFP \> 100 ng/ml);
  • 7\) decompensated cirrhosis;
  • 8\) Serious diseases such as heart, brain, lung, kidney, etc. can not participate in long-term follow-up;
  • 9\) There are hormones and / or immunosuppressants and other liver protection drugs.

Key Trial Info

Start Date :

March 1 2018

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

March 30 2019

Estimated Enrollment :

400 Patients enrolled

Trial Details

Trial ID

NCT04028869

Start Date

March 1 2018

End Date

March 30 2019

Last Update

July 23 2019

Active Locations (1)

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liver disease center, Beijing Ditan Hospital

Beijing, Beijing Municipality, China, 100015

Clinical Observation of Long-term Efficacy and Safety of Glycyrrhizic Acid Preparation in the Therapy of Autoimmune Liver Disease | DecenTrialz