Status:
TERMINATED
Immune Activation as a Cause of Insulin Resistance in Adults Living With HIV-1 on Effective Antiretroviral Therapy
Lead Sponsor:
University Hospital, Montpellier
Conditions:
HIV Infections
Eligibility:
All Genders
18+ years
Brief Summary
The aim of this study is to characterize in non-viremic HIV-1 patients under antiretroviral therapy an immune activation profile that the investigators have previously shown to be strongly linked to h...
Detailed Description
The working hypothesis of this study is that in efficiently treated HIV patients, various profiles of immune activation may be distinguished, each favouring particular comorbidities. Using a panel of ...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- Subject consulting or hospitalized in the tropical and infectious diseases unit at the University Hospital of Montpellier that have been enrolled in a study during which the immune activation profile was analyzed
- Subject aged at least 18 years
- Subject speaking french fluently
- Subject who is not opposed to participate to the study, after a clear information
- Subject affiliated to a social security system
- Infection by HIV-1 determined by a positive serology or by a measure of the plasma viral load (RNA HIV)
- HIV-1 patients under stable antiretroviral therapy
- HIV load \< 50 copies/mL since at least 6 months before enrollment (2 measures)
- Exclusion criteria:
- Vulnerable individuals
- Persons protected
- Pregnant women or breastfeeding mothers
- Bad understanding of the nature and goals of the study and/or communication difficulties with the investigator
- Subject enrolled in an other study with an exclusion period still running
- Non infectious pathology that might be the origin of an immune anomaly
- Treatment by an immune modulator molecule or by chemotherapy in the 60 days before enrollment in the study
Exclusion
Key Trial Info
Start Date :
March 3 2020
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 9 2024
Estimated Enrollment :
148 Patients enrolled
Trial Details
Trial ID
NCT04028882
Start Date
March 3 2020
End Date
February 9 2024
Last Update
August 6 2024
Active Locations (1)
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1
Saint Eloi Hospital, University Hospital of Montpellier
Montpellier, Hérault, France, 34295