Status:
COMPLETED
Reducing Traffic Pollution Exposure Improves Blood Pressure
Lead Sponsor:
UConn Health
Collaborating Sponsors:
National Institute of Environmental Health Sciences (NIEHS)
Conditions:
Air Pollution
Eligibility:
All Genders
40-75 years
Phase:
NA
Brief Summary
This randomized trial assessed the effect of modifying building envelop and level of air filtration on blood pressure over two hour exposure sessions.
Detailed Description
Living close to major roadways is associated with elevated blood pressure (BP) amongst other adverse health effects. There is growing evidence that ultrafine particles (UFP, \<100 nm in diameter), whi...
Eligibility Criteria
Inclusion
- The inclusion criterion was age 40-75 years.
- There was a preference for people who were otherwise healthy, but overweight or obese.
Exclusion
- A history of a major cardiovascular outcome (including myocardial ischemia (MI), stroke, angina)
- Other serious health problems (current asthma or COPD)
- Taking anti-hypertensive medications
- Smoking or living with a smoker
- Cognitive impairment
- Working at a job with high combustion exposure (taxi/truck driver, restaurant cook)
- High combustion exposure in the preceding 24 hours (driving on the highway, cooking in a restaurant, driving a truck)
- Not speaking English or Chinese.
Key Trial Info
Start Date :
March 1 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 15 2018
Estimated Enrollment :
77 Patients enrolled
Trial Details
Trial ID
NCT04029129
Start Date
March 1 2018
End Date
June 15 2018
Last Update
September 28 2023
Active Locations (1)
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1
University of Connecticut
Farmington, Connecticut, United States, 06030