Status:

COMPLETED

Optoacoustic Images Versus Imagio® Ultrasound

Lead Sponsor:

Seno Medical Instruments Inc.

Conditions:

Breast Cancer

Eligibility:

FEMALE

18+ years

Phase:

NA

Brief Summary

The Imagio® Pivotal Study is intended to evaluate if the results observed in the previous Feasibility Study can be confirmed for pre-specified effectiveness endpoints. Using Intention-to-Diagnose (ITD...

Detailed Description

This will be a controlled, blinded, multi-reader, multi-case (MRMC) study using a sequential design. The study will include 15 readers with an additional 5 as back-up readers depending on qualificatio...

Eligibility Criteria

Inclusion

  • One analyzable mass per patient: BI-RADS 3 and 4a, 4b, 4c and 5 masses as declared by clinical site investigator via PIONEER study inclusion criteria and categorized as BIRADS 3, 4a, 4b 4c and 5 by conventional diagnostic ultrasound (CDU)
  • Masses declared to be in the PIONEER Intention to Diagnose (ITD)/analysis population, including high risk cases per original PIONEER protocol
  • Patient age, indication for study entry and available medical history
  • Evaluable mammograms and OA and IUS video loops and stills for each mass

Exclusion

  • Critical missing IUS or OA still image and/or video loop views or incorrect IUS or OA stills and video loops that would preclude a case from being evaluated by readers
  • Reader-02 Proficiency Test and training cases

Key Trial Info

Start Date :

July 30 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 3 2019

Estimated Enrollment :

480 Patients enrolled

Trial Details

Trial ID

NCT04030104

Start Date

July 30 2019

End Date

November 3 2019

Last Update

July 12 2021

Active Locations (1)

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American College of Radiology Center for Research and Innovation

Philadelphia, Pennsylvania, United States, 19103