Status:

COMPLETED

Evaluating Safety and Efficacy of Umbulizer in Patients Requiring Intermittent Positive Pressure Ventilation

Lead Sponsor:

Umbulizer LLC

Conditions:

Respiratory Failure

Respiratory Insufficiency

Eligibility:

All Genders

18-85 years

Phase:

NA

Brief Summary

Randomized, control crossover study comparing Umbulizer's efficacy to traditional mechanical ventilators

Detailed Description

Mechanical ventilators cost tens of thousands of dollars, rendering them difficult for low and middle income countries to procure. Given chronic shortages of these devices in places like Pakistan, pat...

Eligibility Criteria

Inclusion

  • 1\) Patients needing mechanical ventilation

Exclusion

  • Patients with significant airway resistance (i.e. severe chronic obstructive pulmonary disease or asthma) where clinical investigator is concerned about gas trapping or barotrauma
  • Patients with very low lung compliance (i.e. severe acute respiratory distress syndrome or restrictive disease) where clinical investigator is concerned about problems delivering sufficient tidal volume or end expiratory pressure
  • Patients who experienced a myocardial infarction within the last 6 weeks
  • Patients who are determined by a clinical investigator to be too hemodynamically unstable to be enrolled

Key Trial Info

Start Date :

September 4 2018

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 31 2019

Estimated Enrollment :

24 Patients enrolled

Trial Details

Trial ID

NCT04030208

Start Date

September 4 2018

End Date

December 31 2019

Last Update

August 6 2020

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Services Hospital

Lahore, Punjab Province, Pakistan