Status:

COMPLETED

Investigation of the Microbiome of the Cornea in Microbial Keratitis

Lead Sponsor:

Liverpool University Hospitals NHS Foundation Trust

Collaborating Sponsors:

University of Liverpool

Conditions:

Infectious Keratitis

Eligibility:

All Genders

18+ years

Brief Summary

Design: Prospective observational diagnostic study and methods-comparison. Aims: The overall aim of the project is to better define the pathogenic microorganisms in patients with microbial keratitis...

Detailed Description

Microbial keratitis (MK) is an ophthalmological emergency that can lead to sight threatening complications such as corneal scarring, perforation, endophthalmitis and ultimately blindness. The patient ...

Eligibility Criteria

Inclusion

  • All patients aged 18 years and over presenting with unilateral clinically suspected microbial keratitis to St Paul's Eye Unit, Royal Liverpool University Hospital.
  • Patients with keratoconus undergoing cross-linking, subjects with no history of microbial keratitis, subjects with no history of microbial keratitis who are contact lens wearers and subjects with no history of microbial keratitis but who are on eye drop treatment for glaucoma.

Exclusion

  • Patients who are unable to give their informed consent.
  • Patients under the age of 18 years.

Key Trial Info

Start Date :

September 10 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 1 2022

Estimated Enrollment :

219 Patients enrolled

Trial Details

Trial ID

NCT04030403

Start Date

September 10 2019

End Date

December 1 2022

Last Update

January 3 2023

Active Locations (1)

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Liverpool University Hospitals NHS Foundation Trust

Liverpool, United Kingdom, L18 8TX