Status:

UNKNOWN

Pelvic Floor Reconstruction Using Biological Mesh With Negative Pressure Wound Therapy Following ELAPE

Lead Sponsor:

Beijing Chao Yang Hospital

Conditions:

Perineal Wound Complications After ELAPE

Eligibility:

All Genders

18-80 years

Phase:

NA

Brief Summary

Perineal wound healing is a significant challenge after extralevator abdominoperineal excision (ELAPE) due to a high rate of wound breakdown. And it was proved that neoadjuvant radiotherapy significan...

Eligibility Criteria

Inclusion

  • Rectal cancer within 4 cm of the anal verge
  • T3 or T4, as determined by pre-operative MRI examination; patient did receive neoadjuvant chemoradiotherapy
  • Absence of distant metastases
  • Absence of intestinal obstruction

Exclusion

  • T1-T2, as determined by pre-operative MRI before neoadjuvant chemoradiotherapy
  • Distant metastases
  • Intestinal obstruction
  • Pregnancy or lactating
  • Contraindications to surgery
  • A mental disorder

Key Trial Info

Start Date :

July 1 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

July 31 2021

Estimated Enrollment :

66 Patients enrolled

Trial Details

Trial ID

NCT04033484

Start Date

July 1 2019

End Date

July 31 2021

Last Update

February 8 2021

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Zhen Jun. Wang

Beijing, China, 100020