Status:

ACTIVE_NOT_RECRUITING

Acute Cognitive Changes During Atrial Fibrillation Episodes (AFCOG)

Lead Sponsor:

David Brunk, PA-C, MMS

Collaborating Sponsors:

Colorado Cardiac Alliance

Conditions:

Atrial Fibrillation

Cognitive Symptom

Eligibility:

All Genders

35-80 years

Brief Summary

Objectives: * First, to determine if patients with a history of AF have acute measurable changes in cognitive functioning while in an episode of AF. * Second, to collect basic insight into what speci...

Detailed Description

Inclusion Criteria * Subjects who are patients at Colorado Springs Cardiology (CSC) or Penrose-St. Francis Health Services. * Patients who are between 35-80 years of age. * Subjects actively in an ep...

Eligibility Criteria

Inclusion

  • Subjects who are patients at CSC or Penrose-St. Francis Health Services.
  • Subjects actively in an episode of paroxysmal, or persistent AF (who are expected to receive treatment and converted back to normal rhythm (through antiarrhythmic drug therapy, direct current cardioversion, ablation or Maze/Minimally invasive Maze procedure).
  • Subjects with a history of AF who have had \>3 documented episodes of AF over the preceding 12 months and meet all other inclusion/exclusion criteria can pre-enroll. The cognition tests will be administered during the patient's next captured AF episode.

Exclusion

  • Patients who had coronary bypass surgery during their life time.
  • Patients with a previously documented history of post-pump syndrome during their life time.
  • Patients with presence of, or medical diagnosis of Transient Ischemic Attack (TIA) or Cerebral Vascular Accident (CVA).
  • Patients with presence of, or medical diagnosis of cognitive impairment (dementia, multiple sclerosis, traumatic brain injury, etc.).
  • Female patients who are pregnant or post-partum.
  • Individuals unwilling or unable to take an anticoagulant.

Key Trial Info

Start Date :

August 14 2019

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

January 30 2027

Estimated Enrollment :

600 Patients enrolled

Trial Details

Trial ID

NCT04033510

Start Date

August 14 2019

End Date

January 30 2027

Last Update

October 14 2025

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Penrose St. Francis

Colorado Springs, Colorado, United States, 80907