Status:

COMPLETED

A Study on Patients With Chronic Kidney Disease (CKD) to Assess Treatment Experience and Patterns, Effect of the Treatment, Patient Outcomes and Patient Quality of Life

Lead Sponsor:

AstraZeneca

Conditions:

Chronic Kidney Disease

Eligibility:

All Genders

18-130 years

Brief Summary

DISCOVER CKD is an international observational cohort study in patients with CKD, comprising both prospective and retrospective patient cohorts. The study does not attempt to test any specific a prior...

Detailed Description

DISCOVER CKD is an international observational cohort study in CKD patients, comprising both prospective and retrospective patient cohorts. The study does not attempt to test any specific a priori hyp...

Eligibility Criteria

Inclusion

  • For all countries, except Japan: Male or female patients aged 18 years and over. For Japan: Male or female patients aged 20 years and over.
  • First documented diagnostic code (eg, International Classification of Diseases-10) of CKD (Stages 3A, 3B, 4, 5, or end stage renal disease) or two measures of eGFR of \<75mL/min/1.73 m\^2 recorded at least 90 days apart on or after 1 January 2008, or a code for chronic Renal replacement therapy (hemodialysis and peritoneal dialysis), whichever comes first.
  • Provision of written informed consent - specific for prospective data capture.

Exclusion

  • Concurrent participation in any interventional trial at baseline (index) (prospective only). To be implemented based on local regulatory requirements.
  • The patient is undergoing treatment for active cancer, except for non-melanoma skin cancer.
  • Patients with a life expectancy of less than 12 months (prospective only).
  • Diagnosis of cancer on or within the 1-year prior to index (retrospective only).
  • Less than 1-year registration/medical history (pre-index) (retrospective only).

Key Trial Info

Start Date :

September 11 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

June 30 2023

Estimated Enrollment :

1052 Patients enrolled

Trial Details

Trial ID

NCT04034992

Start Date

September 11 2019

End Date

June 30 2023

Last Update

March 6 2024

Active Locations (43)

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Page 1 of 11 (43 locations)

1

Research Site

Riverside, California, United States, 92505-3071

2

Research Site

San Francisco, California, United States, 94110-3518

3

Research Site

Sanford, Florida, United States, 32771

4

Research Site

Sebring, Florida, United States, 33870-1216