Status:

UNKNOWN

CPET in Evaluation of PH in COPD Patients

Lead Sponsor:

Assiut University

Conditions:

COPD

Pulmonary Hypertension Secondary

Eligibility:

All Genders

40-80 years

Brief Summary

* To evaluate the entire course of exercise during CPET in COPD patients. * To study whether CPET, PFTs and arterial blood gases could discriminate between COPD patients with and without PH. * To stud...

Detailed Description

(COPD) is a common cause of pre-capillary pulmonary hypertension (PH). Pulmonary hypertension (PHT) is a common complication of COPD and is determinant for the prognosis of COPD. PHT is defined as A ...

Eligibility Criteria

Inclusion

  • Stable COPD patients
  • with age ≥ 40 years.
  • Prior to inclusion, the COPD diagnosis was verified by spirometry before and after bronchodilation.
  • treatment was optimized and Patients on regular medication.

Exclusion

  • Patients who refuse to participate in the study.
  • Patients underwent thorough pulmonary and cardiologic preinclusion screening, and those with pulmonary disease other than COPD and emphysema.
  • arrhythmia
  • valvular or coronary heart disease
  • left ventricle dysfunction
  • obstructive sleep apnea syndrome
  • pulmonary embolism
  • systemic hypertension ≥160/90 mmHg
  • inflammatory disease
  • hyperthyroidism
  • renal failure
  • inability to exercise (due to orthopedic, neurologic or musculoskeletal problem).

Key Trial Info

Start Date :

October 1 2019

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

October 1 2021

Estimated Enrollment :

50 Patients enrolled

Trial Details

Trial ID

NCT04035148

Start Date

October 1 2019

End Date

October 1 2021

Last Update

July 30 2019

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