Status:
COMPLETED
Echocardiographic Changes After 3-hydroxy Butyrate+Whey Intake
Lead Sponsor:
University of Aarhus
Collaborating Sponsors:
Arla Food Ingredients, Arla Viby.
Aarhus University Hospital Skejby
Conditions:
Cardiac Output
Endotoxemia
Eligibility:
MALE
20-40 years
Phase:
NA
Brief Summary
This study evaluates the cardiovascular effects of adding the ketone body 3-hydroxy butyrate (3-OHB) to whey protein during human endotoxemia. Further, this study compares cardiovascular changes durin...
Detailed Description
Background: A newly published study found beneficial cardiovascular effects of 3-OHB infusion in a population with chronic heart failure, significantly increasing cardiac output. Similar effects on ca...
Eligibility Criteria
Inclusion
- Between 20-40 years of age
- Body mass index between 20-30 kg/m\^2
- Healthy
- Oral and written consent forms obtained prior to study day
Exclusion
- Recent immobilization of an extremity that is not fully rehabilitated
- Lactose, lidocain or rubber allergies
- Current disease
- Use of anabolic steroids
- Smoking
- Former major abdominal surgery (Or current problems with the GI tract)
- •\>10 hours of exercise/weak
- Present ketogenic diets or high-protein diets
- Blood doner that does not want to discontinue blood donations until study completion
- Pending MR scan
Key Trial Info
Start Date :
June 17 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 23 2020
Estimated Enrollment :
8 Patients enrolled
Trial Details
Trial ID
NCT04037722
Start Date
June 17 2019
End Date
January 23 2020
Last Update
June 11 2020
Active Locations (1)
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1
Medical Research Labarotory, DoH, Aarhus University Hospital
Aarhus, Denmark, 8200