Status:
COMPLETED
Long-term Follow-up of Interleukin-1B and H+,K+-ATPase mRNA Expression After Helicobacter Pylori Eradication
Lead Sponsor:
Seoul National University Bundang Hospital
Conditions:
Helicobacter Pylori Infection
Eligibility:
All Genders
18+ years
Brief Summary
We will evaluate the long-term changes of gastric H+, K+-adenosine triphosphatase (H+, K+-ATPase) and Interleukin-1B mRNA expression according to Helicobacter pylori (H.pylori) infection and intestina...
Detailed Description
H. pylori suppresses gastric acid secretion by repressing gastric acid pump, H+, K+-ATPase, and stimulating Interleukin-1B. In this study, we will evaluate the expression of H+, K+-ATPase and Interleu...
Eligibility Criteria
Inclusion
- Controls who did not have any evidence of gastric cancer, gastric dysplasia, esophageal tumor, peptic ulcer and lymphoma on esophagogastroduodenoscopy
- Patients with gastric dysplasia or gastric cancer who diagnosed with gastric dysplasia or early gastric cancer in the final pathological report
Exclusion
- Subjects with previous eradication treatment for H. pylori
- Subjects with previous gastrectomy
Key Trial Info
Start Date :
February 1 2006
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2022
Estimated Enrollment :
490 Patients enrolled
Trial Details
Trial ID
NCT04037904
Start Date
February 1 2006
End Date
December 1 2022
Last Update
April 13 2023
Active Locations (1)
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1
Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, South Korea, 463-707