Status:
COMPLETED
Effects of Interval Training Effects on Cardiac Fibrosis
Lead Sponsor:
Chang Gung Memorial Hospital
Conditions:
Fibrosis Myocardial
Eligibility:
All Genders
21-80 years
Phase:
NA
Brief Summary
The study aimed to highlight the effect of high-intensity interval training (HIIT) on cardiac fibrosis in cardiac patients. From 2009-2018, cardiac patients with measurements of VO2peak, b-type natriu...
Detailed Description
From January 1, 2009 to December 31, 2018, cardiac patients with stable clinical status for greater than 4 weeks have completed 36 times of HIIT. Subjects with clinical assessments (listed below) befo...
Eligibility Criteria
Inclusion
- Heart failure patients, diagnosed according to the Framingham heart failure diagnostic criteria, with stable clinical status for greater than 4 weeks after conservative treatment or intervention were enrolled in the study.
Exclusion
- Those who were
- \< 20 years
- under anti-coagulant therapy
- unable to exercise \> 1 year owing to non-cardiovascular disease
- pregnant or plan to be pregnant within one year
- plan to have cardiac transplant within 6 months
- uncorrected valvular heart disease related heart failure
- congenital heart disease related heart failure
- Other exercise contraindications：
- unstable angina
- resting systolic blood pressure\> 200 mmHg or resting diastolic blood pressure\> 110 mmHg
- orthostatic blood pressure drop (systolic blood pressure drop \> 20 mmHg)。
- critical aortic stenosis stenosis (peak systolic pressure gradient\> 50 mmHg and aortic valve opening \< 0.75 cm2)。
- acute fever
- uncontrolled uncontrolled atrial or ventricular dysrhythmias
- uncompensated congestive heart failure
- 3-degree AV block)
- acute pericarditis and/or myocarditis
- recent embolism \< 6 months
- thrombophlebitis
- restin ST segment displacement \> 2mm
- patients with uncontrolled diabetes (resting serum glucose \> 300mg/dL or \> 250mg/dL with ketone body) was excluded in the study.
Key Trial Info
Start Date :
August 1 2015
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
July 31 2018
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT04038723
Start Date
August 1 2015
End Date
July 31 2018
Last Update
July 31 2019
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.