Status:
COMPLETED
Add-on HD Hf-tRNS Over Bilateral DLPFC for Treating Patients With Schizophrenia
Lead Sponsor:
Tri-Service General Hospital
Conditions:
Schizophrenia
Schizoaffective Disorder
Eligibility:
All Genders
20-65 years
Phase:
NA
Brief Summary
The study aimed to investigate the effects of high-definition transcranial random noise stimulation over bilateral prefrontal cortex on psychopathological symptoms, other clinical outcomes, autonomic ...
Detailed Description
Negative symptoms of schizophrenia include blunted affect, avolition-apathy, alogia and anhedonia-asociality and are closely linked to neurocognitive deficits. Negative symptoms and neurocognitive imp...
Eligibility Criteria
Inclusion
- Eligible participants aged 20-65 with DSM-V-defined schizophrenia or schizoaffective disorder.
- Duration of illness ≧ 1 year.
- Being on an adequate therapeutic dose of antipsychotics for at least 8 weeks prior to enrolment.
- Positive and Negative Syndrome Scale (PANSS scale) total score \< 120 (at both screening and baseline).
- Agreement to participate in the study and provide the written informed consent.
Exclusion
- Having current psychiatric comorbidity or active substance use disorder, in exception to caffeine and/or tobacco.
- Having a history of seizures.
- Having contraindications for transcranial electrical stimulation or transcranial magnetic stimulation, e.g., implanted brain medical devices or metal in the head.
- Having a history of intracranial neoplasms or surgery, or a history of severe head injuries or cerebrovascular diseases.
- Pregnancy or breastfeeding at enrollment.
Key Trial Info
Start Date :
October 24 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 17 2019
Estimated Enrollment :
36 Patients enrolled
Trial Details
Trial ID
NCT04038788
Start Date
October 24 2018
End Date
May 17 2019
Last Update
July 31 2019
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Tri-service general hospital
Taipei, Taiwan, 114