Status:
WITHDRAWN
Residual Dental Pulp Tissue and Cord Blood Stem Cells
Lead Sponsor:
University of California, San Francisco
Conditions:
Irreversible Pulpitis
Eligibility:
All Genders
18+ years
Phase:
PHASE2
Brief Summary
The experiments outlined in this proposal are designed to test the hypothesis that the in vivo injection of cord blood stem cells (InvitRx®) into the root canal system will facilitate teeth initially ...
Detailed Description
Patients will be recruited from the various dental clinics at UCSF (student clinic, Advanced Education in General Dentistry clinic, post-graduate endodontics clinic, etc) that meet the inclusion and e...
Eligibility Criteria
Inclusion
- A. Patients must be systemically healthy, Class I dental category. B. Involved teeth must have no periodontal disease detectible by periodontal examination.
- C. Patients must present without radiographic signs of endodontic disease (i.e. no periapical radiolucencies).
Exclusion
- A. Presence of any disease or medication that alters the immune system or interferes with healing ability B. Smokers (more than 10 cigarettes per day) C. External or internal tooth resorption D. Tooth perforation from the pulp cavity through the tip of the root exposing the tissue to material in the oral cavity.
- E. Pregnant or nursing mothers because hormonal factors may influence the condition.
- F. Allergies or adverse reactions to local anesthetic medications G. Patients under the age of 18. H. Patients with an ASA Classification II or higher
Key Trial Info
Start Date :
September 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 28 2020
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT04040127
Start Date
September 1 2019
End Date
February 28 2020
Last Update
July 27 2020
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