Status:

UNKNOWN

IgM-Enriched Immunoglobulin for Neonatal Sepsis

Lead Sponsor:

Fakultas Kedokteran Universitas Indonesia

Conditions:

Neonatal Sepsis, Early-Onset

Very Low Birth Weight Infant

Eligibility:

All Genders

1-1 years

Phase:

PHASE3

Brief Summary

This study compares giving prophylactic IgM enriched Intravenous Immunoglobulin (IVIG) with placebo in 1 hour after birth, in neonates with risk factors of Early-Onset Neonatal Sepsis (EONS). In addit...

Detailed Description

This randomized-controlled trial conducted in Cipto Mangunkusumo Hospital, Jakarta, Indonesia aims to determine the efficacy of prophylactic IgM-Enriched IVIG in preventing EONS. A total of 70 very lo...

Eligibility Criteria

Inclusion

  • Very low birth weight infants (\< 1500 g)
  • Gestational age below 32 weeks
  • Risk of Early-Onset sepsis from maternal and neonate factors
  • Inborn neonates

Exclusion

  • Birth weight \< 600 g
  • Gestational age \< 26 weeks
  • Multiple Congenital Anomaly
  • Neonates with suspected congenital syndrome

Key Trial Info

Start Date :

September 1 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

August 1 2020

Estimated Enrollment :

70 Patients enrolled

Trial Details

Trial ID

NCT04041765

Start Date

September 1 2019

End Date

August 1 2020

Last Update

August 1 2019

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