Status:
COMPLETED
Pulmonary and Ventilatory Effects of Trigger Modulation in Intubated ICU
Lead Sponsor:
University Hospital, Clermont-Ferrand
Conditions:
ICU Patients
Intubation
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Pressure support ventilation allows intubated ICU patients to breathe spontaneously. Among specific settings, the adjustment of the trigger value (or threshold for triggering the ventilator) has not b...
Detailed Description
The use of invasive mechanical ventilation is one of the most frequent therapies in intensive care units (ICUs). There are several types of indications, depending on the failure: essentially neurologi...
Eligibility Criteria
Inclusion
- Age ≥18 years
- Patient hospitalized in the Intensive Care Unit of Clermont-Ferrand's Hospital
- Patients with mechanical invasive ventilation in spontaneous ventilation with inspiratory support (intubation or tracheostomy)
- Trigger level set to minimum
- Patient under sedation compatible with spontaneous ventilation (SV) with inspiratory support (AI) and positive end-expiratory pressure (PEP) Patient calm (RASS between -2 and 0) Consent for participation or consent from patient's next of kin or inclusion according to an emergency procedure Patient benefiting from the French social security scheme
Exclusion
- Refusal to participate in the proposed study
- Contraindication to the installation of a nasogastric tube:
- Severe disorder of uncorrected blood clotting
- Known nasosinus lesion
- Oesophageal varices recently ligated (\<48h)
- Contraindication to the use of the electro-impedancemetry technique by tomography
- Thoracic lesions
- Chest dressings
- Pace-maker / Implantable Defibrillator
- Known lesion of central respiratory centers, including patients with neurological injury
- Patients with Acute Respiratory Distress Syndrome (according to Berlin criteria)
- Patients with restrictive or obstructive pulmonary pathology
- Patients admitted post-operatively for surgery that may affect the diaphragmatic function ( thoracic or abdominal supra-mesocolic)
- Patients with abdominal distention (ileus, intra-abdominal hyperpressure)
- Patient whose BMI is greater than 35 kg.m-2
- Pregnant patient
- Patient under guardianship,
Key Trial Info
Start Date :
April 3 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 31 2023
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT04041817
Start Date
April 3 2019
End Date
January 31 2023
Last Update
February 17 2023
Active Locations (1)
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1
Service de Réanimation Adultes et Soins Continus
Clermont-Ferrand, France, 63000