Status:
COMPLETED
Permanent Cerebral Oxymetry Monitoring for Early Diagnosis and Treatment of Delayed Vasospasm After Subarachnoid Hemorrhage
Lead Sponsor:
University Hospital, Bordeaux
Conditions:
Subarachnoid Hemorrhage
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
Transcranial Doppler ultrasound (TCD) monitoring and CT-scanner perfusion are useful but imperfect tools to identify vasospasm and allow intervention to avoid infarction. Permanent monitoring of cere...
Detailed Description
Delayed vasospasm is a serious complication of aneurismal subarachnoid haemorhage (SAH) significantly influencing morbidity and mortality. Mostly observed between days 4 and 10 after aneurismal ruptur...
Eligibility Criteria
Inclusion
- Men and women
- Age ≥ 18 years
- HSA of aneurysmal etiology less than 4 days before inclusion diagnosed by clinical presentation and emergency imaging
- HSA "severe" defined according to the WFNS ≥ III
- Intubated-ventilated patient or any other reason preventing a contributing neurological examination
- Affiliate or beneficiary of a social security scheme
- Free, informed and written consent signed by the representative
Exclusion
- Age \<18 years
- Significant vasospasm as soon as the detection was detected on the initial imaging
- Possible Neurological Surveillance
- Patient in limitation of active therapeutics or with high probability of soon limitation of active therapeutics
- Intra-parenchymal frontal haematoma limiting the quality of measurement, diagnosed on imaging (Less than 25mm deep from the skin)
- Patient in limitation of active therapeutics or with high probability of soon limitation of active therapeutics
- Adhesive allergy to measuring patches
- Patient under guardianship or safeguard of justice
- Refusal of legal representative
Key Trial Info
Start Date :
October 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 30 2022
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT04042571
Start Date
October 1 2019
End Date
December 30 2022
Last Update
July 24 2025
Active Locations (1)
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1
CHU de Bordeaux
Bordeaux, France, 33 076