Status:

COMPLETED

Diagnostic Performance of Exome Sequencing in Autism Spectrum Disorders

Lead Sponsor:

University Hospital, Rouen

Conditions:

Autism Spectrum Disorder

Eligibility:

All Genders

Brief Summary

Evaluation of the diagnostic performance of exome sequencing in a prospective series of patients with autism spectrum disorders (ASD).

Eligibility Criteria

Inclusion

  • Patient with ASD who has been previously diagnosed by an expert center according to the DSM5 criteria using standardized instruments (ADOS, ADI-R), referred to genetic consultation by the psychiatrist who performed the clinical diagnosis, according to the recommendations of the HAS, and requesting a genetic analysis for medical purposes in this context.
  • Patient over 3 years old
  • Patient affiliated to a social security scheme
  • For minor patients: Holders of the exercise of parental authority who have read and understood the newsletter and signed the consent form
  • For a major patient: Major patient who has read and understood the newsletter and signed the consent form
  • Supervised minor / minor patient: Legal representative who has read and understood the newsletter and signed the consent form
  • Major patient under guardianship: Major patient assisted by his curator or by the judge having read and understood the newsletter and signed the consent form
  • DNA of the patient and parents available

Exclusion

  • Patient who has already benefited from exome sequencing
  • Person deprived of liberty by an administrative or judicial decision
  • Pregnant or lactating woman

Key Trial Info

Start Date :

June 12 2019

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

October 19 2021

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT04043351

Start Date

June 12 2019

End Date

October 19 2021

Last Update

June 6 2025

Active Locations (1)

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DRCI

Rouen, France, 76000