Status:
COMPLETED
Application of Ultrasound Integrated Precision Diagnosis Technology in Prevention of Kidney Disease and Its Progress
Lead Sponsor:
RenJi Hospital
Collaborating Sponsors:
China-Japan Friendship Hospital
Duke University
Conditions:
Diagnostic Imaging
Diagnosis
Eligibility:
All Genders
18-70 years
Brief Summary
In this study, a prospective, randomized and controlled clinical study would be carried out to establish Ultrasound Integrated Precision Diagnosis Technology with elastography as the core technology t...
Eligibility Criteria
Inclusion
- Inclusion criteria
- for A on C group 1.18-70 years old; gender is not limited; 2. Patients who can cooperate with breath-holding, breath-holding and breath-exhaling movements, and communicate without obstacles.
- The informed consent has been signed; 4.Abnormal renal pathology or glomerular filtration rate(GFR) (15 \<GFR\<90 ml/min.1.73 m2) or proteinuria \> 1 g/24 h due to any cause.
- for kidney transplantation
- 18-70 years old; gender is not limited;
- It can cooperate with breath-holding, breath-holding and breath-exhaling movements, and communicate without obstacles.
- The informed consent has been signed;
- Kidney transplant recipients in our hospital from May 2019 to November 2019
- Exclusion criteria
- for A on C group
- Can't cooperate, can't lie down for at least 10 minutes, unconsciousness, severe hypoxia, restlessness need to rescue patients.
- Patients with pregnancy or cancer;
- There are other serious diseases that the researchers do not think it is suitable to participate in this experiment.
- Absolute contraindications of renal puncture, ① Obvious bleeding tendency; ②Severe hypertension (systolic pressure greater than 180 mm Hg or diastolic pressure greater than 115 mm Hg); ③Psychiatric patients or non-cooperating operators and isolated kidney (small kidney) Or relative contraindications of renal puncture: ① Active pyelonephritis, renal tuberculosis, hydronephrosis or pyonephrosis, ②renal abscess or perirenal abscess. ③Renal tumors or renal aneurysms. ④Polycystic kidney or renal cyst. ⑤Kidney position is too high (deep inhalation of the lower pole of the kidney is not below the twelve ribs) or migratory kidney. ⑥Obesity, severe ascites.
- b）for kidney transplantation
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- Can't cooperate, can't lie down for at least 10 minutes, unconsciousness, severe hypoxia, restlessness need to rescue patients.
- Patients with pregnancy or cancer;
- There are other serious diseases that the researchers do not think it is suitable to participate in this experiment.
- Absolute contraindications of renal puncture, ① Obvious bleeding tendency; ②Severe hypertension (systolic pressure greater than 180 mm Hg or diastolic pressure greater than 115 mm Hg); ③Psychiatric patients or non-cooperating operators and isolated kidney (small kidney) Or relative contraindications of renal puncture: ① Active pyelonephritis, renal tuberculosis, hydronephrosis or pyonephrosis, ②renal abscess or perirenal abscess. ③Renal tumors or renal aneurysms. ④Polycystic kidney or renal cyst. ⑤Kidney position is too high (deep inhalation of the lower pole of the kidney is not below the twelve ribs) or migratory kidney. ⑥Obesity, severe ascites.
Exclusion
Key Trial Info
Start Date :
April 29 2019
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 30 2021
Estimated Enrollment :
208 Patients enrolled
Trial Details
Trial ID
NCT04044404
Start Date
April 29 2019
End Date
June 30 2021
Last Update
November 27 2023
Active Locations (2)
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1
Department of nephrology , Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine
Shanghai, Shanghai Municipality, China, 200127
2
China-Japan Friendship Hospital
Beijing, China