Status:
COMPLETED
Curcumin-Simvastatin-EDTA in the Treatment of Periodontitis
Lead Sponsor:
Ain Shams University
Conditions:
Periodontitis
Eligibility:
All Genders
25-50 years
Phase:
PHASE4
Brief Summary
Among the root conditioning materials is the Ethylenediaminetetraacetic acid (EDTA). EDTA exposes the collagen fibers on dentin surfaces and also enhances early cell colonization. Statins have an anti...
Detailed Description
The present study entailed thirty patients having stage II or stage III, Grade A periodontitis with 30 intrabony defects. Patients were divided into three groups; group I was subjected to open flap de...
Eligibility Criteria
Inclusion
- Patient suffering at least a single posterior 2-3 wall periodontal Pocket of depth ≥ 5 mm, attachment loss ≥3 mm, intrabony component ≥3 mm, plaque index ≤1 (Sillness and Loe, 1964) and sulcus bleeding index ≤1 (Mühlemann \& Son, 1971). All these criteria were determined after phase I conventional periodontal therapy.
- Systemically healthy as evidenced by burket's oral medicine health history question questionnaire (Glick et al., 2008).
- Patients available during follow-up periods
Exclusion
- Smoking
- Patient unwilling to comply with periodontal hygienic instructions
- Patients under any long-term chronic medication
- Vulnerable individuals
Key Trial Info
Start Date :
August 25 2016
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 3 2018
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT04044417
Start Date
August 25 2016
End Date
October 3 2018
Last Update
August 7 2019
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