Status:
RECRUITING
Impact of Capillary Leak and Hypoalbuminemia on PK/PD of Anidulafungin and Caspofungin in Critically Ill Patients
Lead Sponsor:
Universitaire Ziekenhuizen KU Leuven
Collaborating Sponsors:
KU Leuven
Conditions:
Critically Ill Patients
Eligibility:
All Genders
18+ years
Brief Summary
This prospective study will explore the pharmacokinetic exposure and pharmacodynamics of the echinocandins (caspofungin or anidulafungin) in critically ill patients.
Detailed Description
This non-randomized, monocenter pharmacokinetic study will be carried out in critically ill patients receiving multiple dose treatment with echinocandins (caspofungin or anidulafungin). The pharmacok...
Eligibility Criteria
Inclusion
- Treatment with anidulafungin or caspofungin
- Admitted to an ICU ward
Exclusion
- \< 18 years
- DNR 2 or 3
Key Trial Info
Start Date :
September 21 2012
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2025
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT04045366
Start Date
September 21 2012
End Date
December 31 2025
Last Update
July 3 2024
Active Locations (1)
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1
UZ Leuven
Leuven, Belgium, 3000