Status:

COMPLETED

Near InfraRed Fluorescence Using Indocyanine Green and Magnetic Resonance Lymphography of Lymphatic Transport

Lead Sponsor:

University of Rochester

Conditions:

Rheumatoid Arthritis

Eligibility:

All Genders

18-89 years

Phase:

PHASE1

Brief Summary

Lymphatic transport will be examined using Near InfraRed Indocyanine Green fluorescence imaging (NIR-ICG) and magnetic resonance lymphography (MRL) of the upper extremities. The purpose of the study i...

Detailed Description

Lymphedema from various etiologies (i.e. infection, cancer, surgery, and rheumatoid arthritis) remains a major health concern. Efforts to develop effective treatments for this condition have been limi...

Eligibility Criteria

Inclusion

  • Ability to provide written informed consent.
  • Subjects must be 18 years old or older.

Exclusion

  • Active systemic disorders or inflammatory conditions (i.e., chronic infections with hepatitis B, hepatitis C or HIV) that would confound the study results.
  • Known sensitivity to iodine because of residual iodide in indocyanine green
  • Known sensitivity to gadolinium
  • Any history of kidney disease
  • Pregnant women should not participate; pregnancy tests will not be performed.

Key Trial Info

Start Date :

December 15 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 15 2020

Estimated Enrollment :

2 Patients enrolled

Trial Details

Trial ID

NCT04046146

Start Date

December 15 2019

End Date

March 15 2020

Last Update

September 4 2020

Active Locations (1)

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1

University of Rochester

Rochester, New York, United States, 14642