Status:

UNKNOWN

Microwave vs. Radiofrequency Ablation for Benign Thyroid Nodules: A Multicenter Randomized Controlled Trial Study

Lead Sponsor:

Chinese PLA General Hospital

Conditions:

Benign Thyroid Nodules

Ablation

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

Compared with traditional treatment methods, ultrasound-guided thermal ablation is more targeted, less invasive and more reliable. The study compared microwave ablation and radiofrequency ablation to ...

Detailed Description

Ultrasound-guided minimally invasive treatment has accurate positioning, higher targeting, no need for general anesthesia, less trauma for patients, and more reliable efficacy.Currently, it mainly inc...

Eligibility Criteria

Inclusion

  • Age\>18 years and ≤75 years
  • The pathological diagnosis was benign thyroid nodules within 6 months
  • Diameter ≥2cm, solid \> 80%, the number of multiple nodules≤ 3
  • Participate voluntarily and sign the informed consent

Exclusion

  • Coagulation mechanism disorder or bleeding tendency
  • Patients with severe cardiopulmonary insufficiency
  • Blood pressure cannot be effectively controlled
  • abnormal liver function
  • Blood glucose cannot be effectively controlled
  • Abnormal thyroid function
  • Allergic history of ultrasound contrast agent
  • Suspicious lymph node metastasis in the cervical region
  • Abnormal contralateral vocal cord function
  • Pregnant and lactating women
  • Have participated in clinical trials of any drug and/or medical device within 3 months prior to enrollment
  • The researchers believe that there are any other factors that are not suitable for inclusion or that affect participants' participation in the study.
  • Patients with inner pacemaker, hearing aid, metal stent, titanium clip, internal (external) steel plate and other metal objects.

Key Trial Info

Start Date :

August 1 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 31 2021

Estimated Enrollment :

149 Patients enrolled

Trial Details

Trial ID

NCT04046354

Start Date

August 1 2019

End Date

December 31 2021

Last Update

March 3 2021

Active Locations (1)

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Chinese PLA General Hospital

Beijing, Beijing Municipality, China, 100853