Status:

UNKNOWN

A Modified Mathematical Model to Calculate Power Received by Mechanically Ventilated Patients With Different Etiologies

Lead Sponsor:

Changhua Christian Hospital

Conditions:

Acute Respiratory Distress Syndrome, Mechanical Ventilation, Respiratory Mechanics, Ventilator-induced Lung Injury

Eligibility:

All Genders

20-90 years

Brief Summary

Ventilator-induced lung injury is a common complication. The latest and most noticeable theory of its pathogenesis is called 'ergotrauma' by Gattinoni in 2016. The theory uses ventilator-imposed 'ener...

Eligibility Criteria

Inclusion

  • Intubated patients aged 20 to 90 years old

Exclusion

  • Fraction of inspired oxygen (FiO2) higher than 60%
  • Acute physiology and chronic health evaluation (APACHE) II score more than 30
  • Plateau pressure or peak airway pressure more than 30 cmH2O
  • High risk for barotrauma
  • Unstable hemodynamic status
  • Under airway pressure release ventilation or high frequency oscillation ventilation therapy
  • Under extra-corporeal membrane oxygenation support
  • On prone position

Key Trial Info

Start Date :

August 15 2019

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

June 30 2022

Estimated Enrollment :

100 Patients enrolled

Trial Details

Trial ID

NCT04046380

Start Date

August 15 2019

End Date

June 30 2022

Last Update

January 23 2020

Active Locations (1)

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1

Medical Intensive Care Unit

Changhua, Taiwan, 500