Status:
UNKNOWN
Neuroimaging Biomarkers Toward a Personalized Upper Limb Action Observation Treatment in Chronic Stroke Patients
Lead Sponsor:
IRCCS San Raffaele
Collaborating Sponsors:
Casa di Cura del Policlinico di Milano
Conditions:
Chronic Stroke
Eligibility:
All Genders
18-80 years
Phase:
NA
Brief Summary
Much recent interest was raised by the use of Action Observation Treatment (AOT) in stroke patients rehabilitation. AOT, well-grounded in neurophysiology, is an updated approach, based on mirror neuro...
Detailed Description
This study protocol provides 3 experimental designs to satisfy 3 different specific aims as follows. Experimental design aim 1: To assess which kind of ADL visual stimuli will be most effective indu...
Eligibility Criteria
Inclusion
- chronic stroke (never experienced AOT);
- first-ever unilateral stroke due to ischemia provoking a clinically evident upper limb/hand deficit;
- diagnosis verified by brain imaging (MRI);
- cognitive function sufficient to understand the experimental instructions
- Chedoke-McMaster stroke Assessment Scale score greater than 1;
- informed written consent to participate in the study.
Exclusion
- bilateral impairment,
- severe sensory deficits in the paretic upper limb,
- cognitive impairment or behavioral dysfunction,
- refusal or inability to provide informed consent and
- other current severe medical problems.
Key Trial Info
Start Date :
July 1 2019
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 30 2023
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT04047134
Start Date
July 1 2019
End Date
January 30 2023
Last Update
August 3 2022
Active Locations (2)
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1
Casa di Cura del Policlinico di Milano
Milan, MI, Italy
2
IRCCS San Raffaele Pisana
Rome, RM, Italy, 00166