Status:
UNKNOWN
Relationship Between Fractional Flow Reserve/ Instantaneous Wave Free Ratio and Endothelial Wall Shear Stress
Lead Sponsor:
A.O.U. Città della Salute e della Scienza
Collaborating Sponsors:
Politecnico di Torino
Conditions:
Stable Angina
Acute Coronary Syndrome
Eligibility:
All Genders
18-90 years
Brief Summary
This study, designed as a retrospective registry, aims to investigate the relationship and potential interplay between fractional flow reserve (FFR) or instantaneous waves free ratio (iFR) with wall s...
Detailed Description
BACKGROUND AND RATIONALE Despite great advances in atherothrombosis science, the complex interplay of factors leading to plaque progression remains elusive. Specifically, the dynamics leading a stable...
Eligibility Criteria
Inclusion
- Angiography performed for suspected symptom/ischemia-driven stable coronary artery disease or for acute coronary syndromes
- At least one lesion with 30-90% diameter stenosis at invasive angiography with FFR/iFR assessed (for patients with acute coronary syndromes, the invasive assessment will be performed on non-culprit stenosis
- Patient informed consent for data collection and publication in anonymous studies
Exclusion
- Quality of angiographic frames not sufficient for 3D-reconstruction and/or computations
- Patients denying informed consent
Key Trial Info
Start Date :
January 1 2017
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
December 31 2020
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT04048005
Start Date
January 1 2017
End Date
December 31 2020
Last Update
August 7 2019
Active Locations (3)
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1
Ospedale di Rivoli
Rivoli, Italy, 10098
2
AOU Città della Salute e della Scienza di Torino
Torino, Italy, 10126
3
Ospedale San Giovanni Bosco
Torino, Italy, 10144