Status:
UNKNOWN
Circulating Tumor Cells (CTC) Before and After Thoracic Resection With and Without Intraoperative Use of ExtraCorporeal Membrane Oxygenator(ECMO) or Cardio Pulmonary By Pass (CPB)
Lead Sponsor:
European Institute of Oncology
Conditions:
Thoracic Surgery
Cardiopulmonary Bypass
Eligibility:
All Genders
18+ years
Brief Summary
The role of circulating tumor cells (CTC) in patients suffering from lung cancer and thoracic malignancies is not well known and it is still widely debated. The use of intraoperative cardiorespiratory...
Detailed Description
Background and Rationale: Locally advanced pulmonary and mediastinal cancers invading vital structure such as heart, great vessels, or carina cancer are generally considered as unresectable and incur...
Eligibility Criteria
Inclusion
- Thoracic resection (lung and or mediastinal resection) requiring intraoperative Extra Coprporeal Membrane Oxygenator (ECMO) or Cardio Pulmonary By pass (CPB) support; in the control group same disease and planned procedure to be performed without the need of EMCO or CPB.
- Infiltration of the main carina
- Infiltration of superior vena cava
- Single lung surgery
- Mediastinal involvment
Exclusion
- Age younger than 18 years
- Contraindications to general anesthesia
- Poor general clinical conditions ( ECOG PS \>=2)
- Patients unable to provide informed consent
Key Trial Info
Start Date :
August 22 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
October 30 2023
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT04048512
Start Date
August 22 2019
End Date
October 30 2023
Last Update
June 28 2023
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
European Institue of Oncology
Milan, Italy, 20143