Status:

COMPLETED

NT-proBNP Levels and Obesity in Pregnancy

Lead Sponsor:

Duke University

Conditions:

Obesity

Pregnancy Complications

Eligibility:

FEMALE

18+ years

Brief Summary

A screening modality to help categorize obese pregnant women as high or low probability for heart failure would be helpful in the evaluation of the obese pregnant women with dyspnea. Outside of pregna...

Detailed Description

This study is a prospective, cross-sectional observational study of pregnant women \>= 18-years-old receiving prenatal care through the Duke University Health System. Potential study subjects will be ...

Eligibility Criteria

Inclusion

  • Eligibility criteria Third-trimester pregnancy (≥27 weeks)
  • Exclusion criteria Age ≥ 18 years English-speaking Fetal complications
  • Fetal anomalies
  • Intrauterine fetal demise
  • Fetal growth restriction (\<5%ile)
  • Fetal aneuploidy Maternal complications
  • Chronic hypertension (diagnosis pre-dating pregnancy or BP ≥140/90 at \<20 weeks gestation)
  • Autoimmune disorders (systemic lupus erythematosus, rheumatoid arthritis, Sjogren's)
  • Baseline renal disease (baseline Cr \>1.0)
  • Pre-existing diabetes mellitus
  • History of cardiomyopathy or heart failure
  • History of cardiac arrest or myocardial infarction

Exclusion

    Key Trial Info

    Start Date :

    July 15 2019

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    July 1 2020

    Estimated Enrollment :

    56 Patients enrolled

    Trial Details

    Trial ID

    NCT04049136

    Start Date

    July 15 2019

    End Date

    July 1 2020

    Last Update

    August 5 2020

    Active Locations (1)

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    Duke Perinatal Durham Clinic

    Durham, North Carolina, United States, 27705