Status:
UNKNOWN
Diagnosis of Lung Complication After Allo-HSCT by Multiple Parameter System Through BAL
Lead Sponsor:
Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine
Conditions:
Bronchoalveolar Lavage Fluid
Lung Infection
Eligibility:
All Genders
18-70 years
Brief Summary
The aim of this study was to evaluate the diagnostic yield for lung complication after allo-HSCT by multiple parameter system through BAL.
Detailed Description
一) Adult patients with hematology disease under allo-HSCT at any phase of treatment are enrolled according to the following criteria: 1. lung infiltration detection at computed tomography (CT) scan. ...
Eligibility Criteria
Inclusion
- Diagnosed with hematological diseases.
- Recipients of allogeneic peripheral blood stem cell transplantation.
- Lung infiltration detection at computed tomography (CT) scan.
- Patients with fever, cough, respiratory symptoms.
- Consent to BAL and follow-up observation after BAL
Exclusion
- Severe bleeding tendency, platelet less than 20000/uL, or severe coagulation dysfunction;
- Multiple bullae are at risk of rupture;
- Untreated patients with active pulmonary tuberculosis;
- Patients with severe consumptive diseases or conditions and various causes can not cooperate well
- Cardiac insufficiency, severe pulmonary ventilation dysfunction
- Recent massive hemoptysis
- Aortic aneurysm and esophageal varices are at risk of rupture
Key Trial Info
Start Date :
August 30 2019
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
March 30 2022
Estimated Enrollment :
250 Patients enrolled
Trial Details
Trial ID
NCT04051372
Start Date
August 30 2019
End Date
March 30 2022
Last Update
August 9 2019
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