Status:
COMPLETED
Assesment of Gingival Crevicular Fluid and Serum ErbB4/Neuregulin-4 Levels in Periodontal Disease and Health
Lead Sponsor:
Abant Izzet Baysal University
Conditions:
Periodontitis
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
This study aimed to investigate gingival crevicular fluid (GCF) and serum ErbB4 and Nrg4 levels in periodontal health and disease. A total of 80 individuals, 20 patients with stage II grade B periodon...
Detailed Description
A total of 80 individuals, comprising 20 patients with stage II grade B periodontitis (P1 Group), 20 patients with stage III grade B periodontitis (P2 Group), 20 patients with gingivitis (G Group), an...
Eligibility Criteria
Inclusion
- Aged \>18 years,
- Having at least 16 natural teeth (excluding third molar),
- Not having any diagnosed medical illness or drug intake that could affect the periodontal condition.
Exclusion
- Patients who had taken antibiotics, nonsteroidal antiinflammatory or any other drugs within the past 3 months,
- Patients received nonsurgical or surgical periodontal treatment,
- Patients who have a restorative and endodontic therapy requirement,
- Having a removable partial denture and/or having orthodontic therapy,
- Current pregnancy or lactation,
- Obesity,
- Heavy smoking and having serum CRP \> 3mg/L .
Key Trial Info
Start Date :
April 2 2018
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 18 2019
Estimated Enrollment :
80 Patients enrolled
Trial Details
Trial ID
NCT04051385
Start Date
April 2 2018
End Date
January 18 2019
Last Update
August 9 2019
Active Locations (1)
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1
Bolu Abant Izzet Baysal University
Bolu, Turkey (Türkiye), 14030