Status:
UNKNOWN
Do Combinatorial Training Lead to Better Cognition and Daily Participation in TBI Persons With Cognitive Impairments
Lead Sponsor:
Chang Gung Memorial Hospital
Conditions:
Trauma, Brain
Cognitive Deficit
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
The objectives of this study are to: (1) determine the effects of combinatorial training (i.e. combinatory of aerobic exercise with cognitive training and guiding training) vs. the sequential training...
Detailed Description
Cognitive deficits and dysfunction in daily participation are common in patients with traumatic brain injury. Previous studies have reported positive effects on cognitive function after computerized c...
Eligibility Criteria
Inclusion
- (1) first episode non-progressive traumatic brain injury at least six months;
- (2) Age range from 18 to 65 years;
- (3) Rancho Los Amigo Level of Cognitive Functioning Scale (LOCF) = 7;
- (4) Montreal cognitive assessment (MOCA) \< 26;
- (5) Self- or informant-reported memory or cognitive complaints;
- (6) Able to follow the study instruction;
- (7) Adequate cardiopulmonary function to perform aerobic exercise;
- (8) Able to walk with or without assistive devices.
Exclusion
- (1) Unstable medical history (e.g., recent myocardial infarction) that might limit involving the training process;
- (2) Concomitant with other neurological disorders (e.g., Parkinson's disease, amyotrophic lateral sclerosis, multiple sclerosis);
- (3) Current participation in another interventional trial.
Key Trial Info
Start Date :
June 3 2020
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
January 1 2022
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT04051528
Start Date
June 3 2020
End Date
January 1 2022
Last Update
June 21 2021
Active Locations (1)
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1
Chang Gung Memorial Hospital
Taoyuan District, Taiwan, 333