Status:
COMPLETED
Hemodynamic Response and Motor Functions Following Transcranial Direct Current Stimulation in Acute Stroke
Lead Sponsor:
Mahidol University
Collaborating Sponsors:
National Research Council of Thailand
Conditions:
Stroke
Acute
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
The aim of the present study is to evaluate the possible effect of using dual-tDCS applied before conventional physical therapy on motor functions and hemodynamic response
Detailed Description
It is generally accepted that transcranial direct current stimulation (tDCS) can induce change in cortical excitability and thus modulate brain plasticity in the human brain. tDCS has been used in neu...
Eligibility Criteria
Inclusion
- Between 18 and 75 years of age
- First ever-acute ischemic unilateral stroke in the anterior circulation (ACA or MCA territory), MRI/CT scan result is thus required.
- Stroke onset from 2-10 days
- Good level of consciousness (alert)
- Free of any neurological antecedent, unstable condition that may increase the risk of stimulation such as epilepsy; although tDCS is believed to induce less or no risk of seizure and epileptic seizure have never been reported in tDCS study even in a study with active epilepsy (19).
- No significant carotid artery occlusive disease (\< 50% internal carotid artery stenosis) as assessed by carotid duplex ultrasonography
- Modified Ranking Scale ≤ 4
Exclusion
- Recurrent stroke
- Having score more than 20 points on the National Institute of Health Stroke Scale
- Be unable to understand the instruction.
- Presence of intracranial metal implantation, cochlear implant, or cardiac pacemaker.
- Having as excessive pain in any joint of the lower limb (numerical pain rating score \> 7)
- Open wound or wound infraction on scalp
Key Trial Info
Start Date :
August 6 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 31 2021
Estimated Enrollment :
96 Patients enrolled
Trial Details
Trial ID
NCT04051658
Start Date
August 6 2019
End Date
December 31 2021
Last Update
June 22 2022
Active Locations (1)
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1
Faculty of Physical Therapy, Mahidol University
Salaya, Nakonpathom, Thailand, 73170