Status:
COMPLETED
Glycemic Index/Saturated Fatty Acid Diet and Hepatic Fat
Lead Sponsor:
Maastricht University Medical Center
Collaborating Sponsors:
Unilever R&D
Conditions:
Fatty Liver, Nonalcoholic
Diet, Healthy
Eligibility:
All Genders
45-75 years
Phase:
NA
Brief Summary
Excessive fat in the liver is associated with impairments in metabolic health. Reducing the amount of carbohydrates and fat both have been shown to reduce liver fat. However, not only the amount fats ...
Detailed Description
Rationale: Excessive fat in the liver is associated with impairments in metabolic health. Reducing the amount of carbohydrates and fat both have been shown to reduce liver fat. However, not only the ...
Eligibility Criteria
Inclusion
- Caucasian
- Male or postmenopausal female
- Aged 45-75 years at start of the study
- Body mass index (BMI) 27 - 38 kg/m2
- Stable dietary habits (no weight loss or gain \>3kg in the past 3 months) Sedentary lifestyle (not more than 2 hours of sports per week)
- TG between 1.0 and 4.0 mmol/L
Exclusion
- Type 2 diabetes
- Any acute condition, exacerbation of chronic condition, or medical history that would in the investigator's or dependent physician's opinion interfere with the study
- Contra-indication for MRI (which can be found in appendix II)
- Alcohol consumption of \>2 servings per day
- Smoking
- Use of medication known to interfere with the safety of study procedures
Key Trial Info
Start Date :
July 22 2019
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 23 2021
Estimated Enrollment :
13 Patients enrolled
Trial Details
Trial ID
NCT04054297
Start Date
July 22 2019
End Date
March 23 2021
Last Update
July 20 2021
Active Locations (1)
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1
Maastricht University
Maastricht, Netherlands, 6229 ER