Status:

RECRUITING

FAZA PET/MRI in CLI Patients Pre and Post Revascularization

Lead Sponsor:

University Health Network, Toronto

Conditions:

Critical Limb Ischemia

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

Peripheral artery disease is a worldwide problem, leading to high mortality and mobility. Critical limb ischemia (CLI) is associated with high risk of amputation with the subsequent decreased in life...

Eligibility Criteria

Inclusion

  • Age \>= 18 years;
  • Patients with clinical evidence of critical limb ischemia that are candidates for revascularization treatment;
  • A negative urine or serum pregnancy test in women of child-bearing age;
  • Ability to provide written informed consent to participate in the study.

Exclusion

  • Contraindication for MR as per current institutional guidelines;
  • Inability to lie supine for at least 30 minutes;
  • Pregnant or breastfeeding;
  • Unable or unwilling to provide informed consent;
  • Impending amputation within 6 weeks of presentation;
  • Previous metallic hardware in the lower limbs;
  • Unable to have ethanol.

Key Trial Info

Start Date :

August 31 2019

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

December 1 2025

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT04054609

Start Date

August 31 2019

End Date

December 1 2025

Last Update

March 30 2025

Active Locations (1)

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1

University Health Network

Toronto, Ontario, Canada, M5G 2N2