Status:

COMPLETED

Study of the Imaging Agent 18F-Var3 in Patients With Breast Cancer

Lead Sponsor:

Memorial Sloan Kettering Cancer Center

Conditions:

Breast Cancer

Eligibility:

FEMALE

18+ years

Phase:

PHASE1

Brief Summary

The purpose of this study is to measure the safety of the investigational imaging agent, 18F-Var3 and to determine if it is helpful in providing information about how tumor tissues behave.

Eligibility Criteria

Inclusion

  • Age 18 years or greater
  • Biopsy-proven breast malignancy
  • \>/= 1 viable lesion, \>/= 1 cm, confirmed on CT, MR, or FDG PET/CT within 4 weeks of protocol enrollment
  • Newly diagnosed or recurrent disease, on or off therapy
  • ECOG performance of 0-2 \*Note: Lesions are considered viable if they are stable or increasing soft tissue lesions, or if they are FDG-avid bone lesions

Exclusion

  • Life expectancy \< 3 months
  • Pregnancy or lactation
  • Biopsy or other surgical procedures within 48 hours prior to receiving study intervention
  • Patients who cannot undergo PT/CT scanning because of weight limits. PET/CT scanners may not be able to function with patients over 400 pounds

Key Trial Info

Start Date :

August 9 2019

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 18 2020

Estimated Enrollment :

6 Patients enrolled

Trial Details

Trial ID

NCT04054986

Start Date

August 9 2019

End Date

September 18 2020

Last Update

May 16 2025

Active Locations (1)

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1

Memorial Sloan-Kettering Cancer Center

New York, New York, United States, 10065