Status:
COMPLETED
Neurobiological Mechanisms of Chess as an Add-On Treatment Against SUD
Lead Sponsor:
Central Institute of Mental Health, Mannheim
Conditions:
Substance Use Disorders
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
Neurobiological and neuropsychological approaches to investigate the potential mechanism of action of chess as an add-on therapy (chess based - cognitive remediation treatment, CB-CRT) to reduce cogni...
Detailed Description
The study aims to investigate the potential mechanism of action of chess as a "chess based - cognitive remediation treatment, CB-CRT" to reduce cognitive deficits in individuals with substance use dis...
Eligibility Criteria
Inclusion
- severe alcohol (AUD) or tabacco use disorder (SUD) according to DSM-5
- abstinence from alcohol for at least 72 hours (AUD)
- sufficient ability to communicate with investigators and answer questions in both written and verbal format
- ability to provide fully informed consent and to use self-rating scales
- main diagnosis AUD: inpatient or outpatient treatment in our clinic
- main diagnosis TUD: participation in 6 weeks smoking cessation treatment
- Normal or corrected to normal vision
- Signed consents for data security
Exclusion
- severe internal, neurological, and/or psychiatric comorbidities; other Axis I mental disorders other than TUD according to ICD-10 and DSM 5 (except for other substance use disorders - if AUD or TUD is still the main diagnosis -, ADHD, remitted depression, mild or moderate depression, adjustment disorder, generalized anxiety disorder, phobias, panic disorder or other mild or moderate personality disorders) in the last 12 months
- Severe withdrawal symptoms (CIWA-Ar \> 7; Sullivan et al. 1989)
- alcohol intoxication (\>0‰)
- history of brain injury
- severe cognitive impairments
- common exclusion criteria for MRI (e.g. metal, claustrophobia, pregnancy)
- suicidality or endangerment of others
- positive Covid-19 screening
Key Trial Info
Start Date :
April 1 2020
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 17 2023
Estimated Enrollment :
108 Patients enrolled
Trial Details
Trial ID
NCT04057534
Start Date
April 1 2020
End Date
November 17 2023
Last Update
March 29 2024
Active Locations (1)
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1
Klinik für Abhängiges Verhalten, Zentralinstitut für Seelische Gesundheit
Mannheim, Germany